Repaglinide EP IMpurity A

Repaglinide EP IMpurity A - Names and Identifiers

Name	4-(Carboxymethyl)-2-ethoxybenzoic acid
Synonyms	Repaglinide EP IMpurity A Repaglinide EP Impurity F 4-(CarboxyMethyl)-2-ethoxybenzoic acid 4-(carboxyMethyl)-3-ethoxybenzoic acid (4-Carboxy-3-ethoxy)phenyl Acetic Acid 4-(Carboxymethyl)-2-ethoxybenzoic acid Repaglinide Impurity 1(Repaglinide EP Impurity A) Repaglinide Related Compound I ((4-Carboxy-3-ethoxy)phenyl Acetic Acid)
CAS	220438-80-2
InChI	InChI=1S/C11H12O5/c1-2-16-9-5-7(6-10(12)13)3-4-8(9)11(14)15/h3-5H,2,6H2,1H3,(H,12,13)(H,14,15)

Repaglinide EP IMpurity A - Physico-chemical Properties

Molecular Formula	C11H12O5
Molar Mass	224.21
Density	1.319±0.06 g/cm3(Predicted)
Melting Point	140-142?C
Boling Point	428.1±35.0 °C(Predicted)
Solubility	DMSO (Slightly), Methanol (Slightly)
Appearance	Solid
Color	White to Off-White
pKa	3.96±0.10(Predicted)
Storage Condition	-20°C Freezer
Use	This product is only for the inspection of repaglinide related substances.

Repaglinide EP IMpurity A - Introduction

4-(Carboxymethyl)-2-ethoxybenzoic acid, also known as 4-(Carboxymethyl)-2-ethoxybenzoic acid, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
4-(Carboxymethyl)-2-ethoxybenzoic acid is a white crystalline solid that is stable at room temperature. It is slightly soluble in water and highly soluble in organic solvents. The compound has a carboxyl group and an ethoxy group substituted at different positions on the benzene ring, which gives it special chemical properties.

Use:
4-(Carboxymethyl)-2-ethoxybenzoic acid has many uses in the chemical industry. It is often used as a reagent and intermediate in organic synthesis reactions. In addition, it is used in the preparation of biologically active organic compounds and pharmaceuticals.

Method:
4-(Carboxymethyl)-2-ethoxybenzoic acid can be synthesized by ethoxylation. Acetophenone is first esterified with bromoacetic acid to give the ethoxylated product. The ethoxylated product is then reacted with hydrochloric acid under certain conditions to give the final product 4-(Carboxymethyl)-2-ethoxybenzoic acid.

Safety Information:
4-(Carboxymethyl)-2-ethoxybenzoic acid is generally safe under normal conditions of use. However, when handling the compound, appropriate personal protective measures should be taken, such as wearing gloves, goggles and protective clothing. In addition, should be away from the fire and oxidant, avoid contact with strong acid or strong base. In case of accidental contact or misuse, rinse immediately with plenty of water and seek medical attention in time. For specific safety information, it is recommended to consult the safety data sheet of the compound or consult a professional.

Last Update：2024-04-09 20:52:54